Figure 1: Synthetic strategies to access secondary and tertiary alcohols by carbonyl addition reactions. Despite considerable advances, and the abundance of organometallic reagents developed for ...

With the help of zinc reagents, chemists have found a loophole in rules that govern additions to chiral carbonyl compounds, a fundamental reaction in organic synthesis. The work, presented on March 24 ...

Carbonyls (C=O groups) are popular reactive handles. But carbonylation reactions, which create these useful groups by appending carbon monoxide to aryl halides or alkyl halides with the help of a ...

The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...