Calcium channel blocker toxicity represents a significant clinical challenge owing to its multifaceted pathophysiology and potential to precipitate life‐threatening cardiovascular compromise. Overdose ...

Toxicity due to calcium-channel blockers (CCBs) or β-blockers results in significant morbidity and mortality. [9] The manifestations of toxicity are generally extensions of the drugs' pharmacologic ...

When you have atrial fibrillation, the two upper chambers of your heart (atria) don't beat in sync with the two lower chambers (ventricles). This makes your heart beat out of rhythm and sometimes very ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Praxis Precision Medicines' ulixacaltamide (PRAX-944) is a potent and selective small molecule T-type Ca2+ channel blocker being developed for the potential treatment of essential tremor. ET is a ...