Alpha-enolase (ENO1) is a multifunctional enzyme primarily known for its role in glycolysis, where it catalyses the conversion of 2-phosphoglycerate to phosphoenolpyruvate. However, ENO1’s ...

Caveolin-1 (Cav-1) is a principal scaffolding protein that orchestrates the formation of caveolae—specialised lipid microdomains within the plasma membrane. Its functions extend to the regulation of ...

Dr. Anczukow is a leading cancer biologist with expertise in RNA biology, molecular and cell biology, as well as human genetics, cancer biology, and genomics Olga Anczukow, Ph.D. Olga Anczukow, Ph.D.

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

Crystalline polymers assembled inside tumor cell lysosomes rupture membranes, release iron, and trigger immune-activating ...

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes. These droplet-like dynamic assemblies control the way in which DNA is turned into ...

Scientists have uncovered an unexpected reason why some cancers return after initially responding to treatment.

Scientists have identified a mirror-image form of the amino acid cysteine that selectively slows the growth of certain cancers while leaving healthy cells largely unharmed.

Studying gene expression in a cancer patient's cells can help clinical biologists understand the cancer's origin and predict ...

Cells were long believed to safeguard nuclear contents, releasing them only during cell death. Extracellular DNA was thought ...

A growing body of research suggests that three popular anti-aging supplements — NMN, resveratrol, and high-dose folic acid — may be supercharging cancer cell growth through a mechanism called ...

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don't fight them—throw them in the cellular trash. In a new study published in ...