The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

When the body experiences an injury to a blood vessel, muscular response to the injury causes the vessel to constrict, decreasing blood flow to the area. The blood is exposed to collagen in the ...

A DZHK research team at the University Medical Center Mainz has discovered a new signaling pathway of the coagulation system that controls scar formation after a heart attack. If this signaling ...

Studies by researchers at Columbia University Irving Medical Center suggest that one of the immune system’s oldest branches, the complement system, and coagulation dysfunction, may be influencing the ...

When injured, endothelial cells permit granulocytes and plasma constituents to enter inflamed tissue, which may lead to organ damage. Endothelial cell inflammation causes vasodilation through the ...