A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...