There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Like its viral cousins, a somewhat parasitic DNA sequence called a retrotransposon has been found borrowing the cell's own machinery to achieve its goals. In a new work appearing online Wednesday in ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...