*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...

Until recently, protein–protein interactions (PPIs) were seen to present contact surfaces too broad and featureless to give newly developed PPI-modulating drugs much purchase. Developers of such drugs ...

Mass Spec Alternative Detects Biomarker Signatures in Tissues, Blood, and Cell Culture The current generation of antibody microarray technologies is providing highly sensitive new tools for screening ...

Yale University researcher Michael Snyder and his colleagues have created the first microchip able to analyze virtually all yeast proteins, the chemicals that carry out the activities necessary for ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Expression proteomics determines where and when proteins are expressed and measures their quantities. This qualitative and quantitative approach can compare protein expression across conditions, such ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...