Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...

"Our findings help us separate chronic and acute inflammation, as well as identify a new target for stopping chronic inflammation that results from aging and disease." Using chronically inflamed human ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Chronic diseases such as type 2 diabetes and inflammatory disorders are a major cause of disease burden and deaths around the world, but their treatment has proven difficult because there may not be ...

Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...

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A University of California, Riverside-led team has made an advance in the basic understanding of Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, that could ...

Designing drugs is a bit like playing with Polly Pocket. The vintage toy is a plastic clam shell that contains a multi-bedroom house, a skating rink, a disco dance floor, and other fun scenarios. Kids ...