Telomerase promotes proliferation of resting stem cells through a mechanism that does not involve the extension of chromosomal telomeres, researchers report in Nature this week. "This is a completely ...

Study shows how telomerase can run amok, deleteriously capping damaged DNA, were it not for a first responder to DNA damage. The natural ends of chromosomes appear alarmingly like broken DNA, much as ...

Specialized nucleoprotein structures, termed telomeres, cap the ends of human chromosomes. These terminal structures, composed of repetitive arrays of guanine-rich hexameric DNA together with specific ...

The central dogma of molecular biology showing what is happening in this study. Credit: Julian Chen For the very first time, a study led by Julian Chen and his group in Arizona State University's ...

Telomere shortening is a potential diagnostic tool for differentiating ILD types, particularly in idiopathic pulmonary fibrosis (IPF). Genetic mutations in telomerase genes, such as TERC and TERT, ...

Scientists investigate human telomere length to elucidate aging and diseases such as cancer and neurodegenerative disorders. In normal mammalian cells, a small telomeric DNA segment is lost after each ...